Both gout and calcium pyrophosphate dihydrate CPPD arthropathies are crystal deposit diseases; finding monosodium urate MSU or CPPD crystals in a synovial fluid sample, or in a tophi in the case of gout, provide a definitive, unequivocal diagnosis. Despite having such a simple and precise diagnostic test, in both crystal arthitides there is the accepted habit of approaching their diagnosis on clinical grounds accompanied by hyperuricemia for gout, or chondrocalcinosis for the CPPD related arthropathy. Typical clinical presentations suggesting crystal arthitides may be due to other causes, and more important, less typical presentations, which are not uncommon, will pass undiagnosed unless crystals are systematically searched for in a synovial fluid sample from all undiagnosed arthropathies. Finally the precision of a clinical diagnosis made by an expert rheumatologist is higher than that of a less experienced or less specialized physician, and by approaching the diagnosis of the crystal arthritides on clinical grounds, expert rheumatologists support the inaccurate approach of other physicians with a wider margin of error.. ISSN: X. Diagnosis of Microcrystalline Arthropathy.
|Published (Last):||9 September 2009|
|PDF File Size:||5.35 Mb|
|ePub File Size:||4.63 Mb|
|Price:||Free* [*Free Regsitration Required]|
Chondrocalcinosis articularis section L clinical and radiological study. Ann Rheum Dis. Clinical aspects. Ann Inter Med. Reginato AJ. Calcium pyrophosphate dihydrate gout and other crystal deposition diseases.
Curr Opin Rheumatol. Rull M. Calcium crystal-associated diseases and miscellaneous crystals. Joint hypermobility leading to osteoarthrosis and chondrocalcinosis. Abhishek A, Doherty M. Epidemiology of calcium pyrophosphate crystal arthritis and basic calcium phosphate crystal arthropathy.
Rheum Dis Clin North Am. Hereditary chondrocalcinosis in a Mexican-American family. Arthritis Rheum. Med Clin Barc. Relative frequency of gout and pseudogout. Maravic M, Ea HK. Hospital burden of gout, pseudogout and other crystal arthropathies in France.
Joint Bone Spine. Familial chondrocalcinosis in the Chiloe Islands, Chile. Familial osteoarthritis and Milwaukee shoulder associated with calcium pyrophosphate and apatite crystal deposition. J Rheumatol. Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease. Mutations in ANKH cause chondrocalcinosis.
Am J Hum Genet. The role of ANK in calcium pyrophosphate deposition disease. Curr Rheumatol Rep. EULAR recommendations for calcium pyrophosphate deposition. Part II: management. Evidence for a causal relationship between the structure, size, and load of calcium pyrophosphate dihydrate crystals, and attacks of pseudogout.
Methotrexate in chronic-recurrent calcium pyrophosphate deposition disease: no significant effect in a randomized crossover trial.
Arthritis Res Ther. A double-blind randomized controlled trial appraising the symptom-modifying effects of colchicine on osteoarthritis of the knee.
Clin Exp Rheumatol.
2016, Número 3